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CCKBR agonist-1

CAT: 0013-GTR19150417-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19150417-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CCKBRagonist-1 (Compound 3r1) is a selective agonist for the cholecystokinin B receptor (CCKBR) that preferentially activates the Gq protein, with an EC50 of 35 pM. It significantly enhances neuronal survival at an EC50 of 37 pM. CCKBRagonist-1 improves cognitive decline in mice by upregulating α-secretase (ADAM10) and the calcium signaling molecule PLCB4, reduces the number of amyloid β (Aβ) plaques, and promotes long-term potentiation (LTP) . This compound is useful for Alzheimer's disease research.
Molecular Weight
699.6
Notes
For research use only.

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