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SMIP34

CAT: 0804-HY-169903-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-169903-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
SMIP34 is a PELP1 inhibitor. SMIP34 binds to PELP1 with a Kd of 37.4 μM. SMIP34 inhibits cancer cell proliferation and tumor progression. SMIP34 can be used for breast cancer research, and is active against wild-type (WT), mutant (MT) ER+ and therapy-resistant (TR) -ER+ breast cancer[1].
CAS Number
1189710-20-0
UNSPSC
12352005
Target
Apoptosis
Type
Reference compound
Related Pathways
Apoptosis
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/smip34-6.html
Purity
90.0
Smiles
O=C(C1=NN2C(C(N(C(C)(C2)C(NC3CCCC3)=O)CCCC)=O)=C1)NC4=CC=C(C)C(Cl)=C4
Molecular Formula
C25H32ClN5O3
Molecular Weight
486.01
References & Citations
[1]Altwegg KA, et al. A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer. Cancer Res. 2022 Oct 17;82 (20) :3830-3844.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Dedicated for Diverse Library
Clinical Information
No Development Reported

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