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3-Indolepropionic acid (Standard)

CAT: 0804-HY-W015229R-01Size: 25 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-W015229R-01Size:25 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
3-Indolepropionic acid (Standard) is the analytical standard of 3-Indolepropionic acid. This product is intended for research and analytical applications. 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease. In Vitro: 3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease[1]. 3-Indolepropionic acid is a more potent scavenger of hydroxyl radicals than melatonin. Similar to melatonin but unlike other antioxidants, 3-Indolepropionic acid scavenges radicals without subsequently generating reactive and pro-oxidant intermediate compounds[2]. It is also suggested that indolepropionic acid, a gut microbiota-produced metabolite, is a potential biomarker for the development of type 2 diabetes (T2D) that may mediate its protective effect by preservation of β-cell function[3].
CAS Number
830-96-6
Product Name Alternative
Indole-3-propionic acid (Standard) ; 3-IPA (Standard)
UNSPSC
12352005
Target
Endogenous Metabolite; Reactive Oxygen Species (ROS) ; Reference Standards
Type
Reference Standards
Related Pathways
Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Neurological Disease
Assay Protocol
https://www.medchemexpress.com/3-indolepropionic-acid-standard.html
Purity
99.97
Smiles
C1=CC=CC2=C1C(=C[NH]2)CCC(O)=O
Molecular Formula
C11H11NO2
Molecular Weight
189.21
References & Citations
[1]Wikoff WR, et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10;106 (10) :3698-703.|[2]Reiter RJ, et al. Reactive oxygen intermediates, molecular damage, and aging. Relation to melatonin. Ann N Y Acad Sci. 1998 Nov 20;854:410-24.|[3]de Mello VDet al. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Sci Rep. 2017 Apr 11;7:46337. doi: 10.1038/srep46337.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards

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