3-Indolepropionic acid

• Description :

  3-Indolepropionic acid is shown to be a powerful antioxidant and has potential in the treatment for Alzheimer’s disease.

• Product Name Alternative :

  Indole-3-propionic acid; 3-IPA

• UNSPSC :

  12352005

• Hazard Statement :

  H302, H315, H319, H335

• Target :

  Endogenous Metabolite; Reactive Oxygen Species (ROS)

• Type :

  Natural Products

• Related Pathways :

  Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

• Applications :

  Metabolism-sugar/lipid metabolism

• Field of Research :

  Metabolic Disease; Neurological Disease

• Assay Protocol :

  https://www.medchemexpress.com/3-Indolepropionic_acid.html

• Purity :

  99.92

• Solubility :

  DMSO : ≥ 100 mg/mL|H2O : 1 mg/mL (ultrasonic; warming; heat to 80°C)

• Smiles :

  C1=CC=CC2=C1C(=C[NH]2)CCC(O)=O

• Molecular Formula :

  C11H11NO2

• Molecular Weight :

  189.21

• Precautions :

  H302, H315, H319, H335

• References & Citations :

  [1]Wikoff WR, et al. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10;106 (10) :3698-703.|[2]Reiter RJ, et al. Reactive oxygen intermediates, molecular damage, and aging. Relation to melatonin. Ann N Y Acad Sci. 1998 Nov 20;854:410-24.|[3]de Mello VDet al. Indolepropionic acid and novel lipid metabolites are associated with a lower risk of type 2 diabetes in the Finnish Diabetes Prevention Study. Sci Rep. 2017 Apr 11;7:46337. doi: 10.1038/srep46337.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• Isoform :

  Human Endogenous Metabolite; Microbial Metabolite

• CAS Number :

  [830-96-6]