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Enzyme-IN-1

CAT: 0804-HY-150226-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-150226-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Enzyme-IN-1 (compound 1) is a peptide-based inhibitor of N-terminal nucleophile (Ntn) hydrolases. Specifically, Enzyme-IN-1 inhibits the chymotrypsin-like activity (CT-L) of the 20S proteasome. Enzyme-IN-1 may has potential antiinflammatory properties[1].
CAS Number
868540-02-7
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Proteasome
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/enzyme-in-1.html
Concentration
10mM
Purity
95.19
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
OCC(N[C@@H](CCC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C([C@]3(CO3)C)=O)=O)=O)=O)=O
Molecular Formula
C36H50N4O7
Molecular Weight
650.80
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501
References & Citations
[1]Smyth Mark, et al. Preparation of peptides for the inhibition of enzymes. United States, US20050245435 A1. 2005-11-03.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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