DiFMUP

CAT: 0804-HY-120166-01Size: 5 mgDry Ice: NoHazardous: No

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CAT#:0804-HY-120166-01Size:5 mg

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Description

DiFMUP is a fluorogenic substrate, and has been widely used for the continuous detection of phosphatase activities. DiFMUP is hydrolysis by a phosphatase results in the release of Xuorescent DIFMU, which can be easily followed in continuous mode by a Xuorescence reader[1][2].

CAS Number

214491-43-7

Product Name Alternative

6,8-Difluoro-4-methylumbelliferyl phosphate

UNSPSC

12352005

Target

Phosphatase

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/difmup.html

Purity

99.05

Solubility

DMSO : 50 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

O=P(OC1=C(C(OC2=O)=C(C(C)=C2)C=C1F)F)(O)O

Molecular Formula

C10H7F2O6P

Molecular Weight

292.13

References & Citations

[1]Gee KR, et, al. Fluorogenic substrates based on fluorinated umbelliferones for continuous assays of phosphatases and beta-galactosidases. Anal Biochem. 1999 Aug 15;273 (1) :41-8.|[2]Welte S, et, al. 6,8-Difluoro-4-methylumbiliferyl phosphate: a fluorogenic substrate for protein tyrosine phosphatases. Anal Biochem. 2005 Mar 1;338 (1) :32-8.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

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BA8085-25	DiFMUP
79769	SHP-2 Substrate (DiFMUP)

DiFMUP

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