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Sterculic acid

CAT: 0804-HY-127143-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-127143-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Sterculic acid is a stearoyl-CoA desaturase-1 (SCD1) inhibitor. Sterculic acid specifically inhibits the delta-9 desaturase (Δ9D) activity with an IC50 value of 0.9 μM[1].
CAS Number
738-87-4
UNSPSC
12352211
Target
Stearoyl-CoA Desaturase (SCD)
Type
Natural Products
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sterculic-acid.html
Purity
99.0
Solubility
DMSO : < 1 mg/mL (ultrasonic) |Ethanol : < 1 mg/mL (ultrasonic)
Smiles
CCCCCCCCC1=C(C1)CCCCCCCC(O)=O
Molecular Formula
C19H34O2
Molecular Weight
294.47
References & Citations
[1]Lei Zhang, et al. A multiplexed cell assay in HepG2 cells for the identification of delta-5, delta-6, and delta-9 desaturase and elongase inhibitors. J Biomol Screen. 2010 Feb;15 (2) :169-76.|[2]Rafael Peláez, et al. Sterculic Acid: The Mechanisms of Action beyond Stearoyl-CoA Desaturase Inhibition and Therapeutic Opportunities in Human Diseases. Cells. 2020 Jan 7;9 (1) :140.|[3]Abril Ramírez-Higuera, et al. Preventive Action of Sterculic Oil on Metabolic Syndrome Development on a Fructose-Induced Rat Model. J Med Food. 2020 Mar;23 (3) :305-311.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported

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