Recombinant Human PD-1 Protein

CAT: 0013-GTR19124934-01Size: 10 µgDry Ice: NoHazardous: No

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CAT#:0013-GTR19124934-01Size:10 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

Recombinant Human Programmed Cell Death Protein 1 mutant (C93S) is produced by our Mammalian expression system and the target gene encoding Leu25-Gln167 (Cys93Ser) is expressed with a 6His tag at the C-terminus.

Product Name Alternative

Programmed cell death protein 1; PDCD1; PD-1; hPD-1; CD279

UniProt

Q15116

Expression Region

Leu25-Gln167 (Cys93Ser)

Conjugation

Unconjugated

Tag

C-6His

Origin

Human

Field of Research

Cancer Biology

Endotoxin

< 1 EU/μg as determined by LAL test.

Purity

SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.

Bioactivity

BLI: Loaded Anti-Human PD-1 mAb-Fc (Cat#GMP-A085) on Protein A Biosensor, can bind Human PD-1-His (Cat#orb2994332) with an affinity constant of 4.97 nM as determined in BLI assay.

Form

Lyophilized

Molecular Weight

Predicted: 16.8 KDa. Observed: 23-38 KDa, reducing conditions

Storage Conditions

Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.

Notes

For research use only.

Preservative

0.2 μm filtered solution of PBS, pH 7.4.

UniProtKB · Q15116

Programmed cell death protein 1

PDCD1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q15116
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PDCD1
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: Protein PD-1, hPD-1
EC number: —
Processing: Precursor
Secondary accessions: O00517, Q8IX89

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Biological process

Adaptive immunityApoptosisImmunity

Cellular component

Cell membraneMembrane

PTM

Disulfide bondGlycoproteinIsopeptide bondPhosphoproteinUbl conjugation

Domain

Immunoglobulin domainSignalTransmembraneTransmembrane helix

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PROTQ15116-2-100ug	Human recombinant PD-1 protein
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TMPY-04898-01	PD-1 Protein, Human, Recombinant (hFc)
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