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Recombinant Human monomeric alpha-Synuclein Protein

CAT: 0013-GTR19124494-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19124494-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant Human Alpha-Synuclein is produced by our E.coli expression system and the target gene encoding Met1-Ala140 is expressed.
Product Name Alternative
Alpha-Synuclein; Non-A Beta Component of AD Amyloid; Non-A4 Component of Amyloid Precursor; NACP; SNCA; NACP; PARK1
UniProt
P37840
Expression Region
Met1-Ala140
Conjugation
Unconjugated
Tag
Tag free
Origin
Human
Field of Research
Neuroscience
Endotoxin
< 0.001 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE. (QC verified)
Bioactivity
ELISA: Immobilized Recombinant Human SNCA (Cat#orb2994630) at 2μg/ml (100 μl/well) can bind Anti-Human SNCA antibody.The ED50 of Anti-SNCA antibody is 3.11ng/ml. (Regularly tested) . Lot-to-lot Consistency: Three independent lots were tested for activity and plotted on the same graph to show lot-to-lot consistency of alpha-Synuclein (Cat.No.:orb2994630) .
Form
Lyophilized
Molecular Weight
Predicted: 14.46 KDa. Observed: 17 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of PBS, pH 7.4

UniProtKB · P37840

Alpha-synuclein

SYUA_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P37840
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SNCA
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
A8K2A4, Q13701, Q4JHI3, Q6IAU6
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoproteinUbl conjugation

Coding sequence diversity

Alternative splicing

Disease

Alzheimer diseaseDisease variantNeurodegenerationParkinson diseaseParkinsonism

Cellular component

AmyloidCell projectionCytoplasmMembraneNucleusSecretedSynapse

Ligand

CopperMetal-binding

Domain

Repeat

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