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Recombinant Human ApoE3 Protein

CAT: 0013-GTR19124420-01Size: 10 µgDry Ice: NoHazardous: No
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CAT#:0013-GTR19124420-01Size:10 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Recombinant Human Apolipoprotein E3 is produced by our Mammalian expression system and the target gene encoding Lys19-His317 is expressed with a 6His tag at the C-terminus.
Product Name Alternative
Apolipoprotein E; APOE; Apo-E; ApoE3
UniProt
P02649
Expression Region
Lys19-His317
Conjugation
Unconjugated
Tag
C-6His
Origin
Human
Endotoxin
< 1 EU/μg as determined by LAL test.
Purity
SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
Bioactivity
ELISA: Immobilized Recombinant Human ApoE3 (C-6His) (Cat# orb2994564) at 2μg/ml (100 μl/well) can bind Recombinant Human TREM2 (C-Fc) (Cat# orb2993662) . The EC50 of Recombinant Human TREM2 (C-Fc) (Cat# orb2993662) is 41.52ng/ml. (Regularly tested)
Form
Lyophilized
Molecular Weight
Predicted: 35.3 KDa. Observed: 39 KDa, reducing conditions
Storage Conditions
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
Notes
For research use only.
Preservative
0.2 μm filtered solution of 20mM Tris-HCl, 5% Trehalose,5% Mannitol, 0.02% Tween80, pH 8.0.

UniProtKB · P02649

Apolipoprotein E

APOE_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
P02649
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
APOE
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
Apo-E
EC number
—
Processing
Precursor
Secondary accessions
B2RC15, C0JYY5, Q9P2S4
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Disease

Alzheimer diseaseAmyloidosisDisease variantHyperlipidemiaNeurodegeneration

Biological process

Cholesterol metabolismHost-virus interactionLipid metabolismLipid transportSteroid metabolismSterol metabolismTransport

Cellular component

ChylomicronEndosomeExtracellular matrixHDLSecretedVLDL

PTM

GlycationGlycoproteinOxidationPhosphoprotein

Molecular function

Heparin-binding

Ligand

Lipid-binding

Domain

RepeatSignal

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