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HL2-m5

CAT: 0013-GTR19113286-01Size: 50 mgDry Ice: NoHazardous: No
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CAT#:0013-GTR19113286-01Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
HL2-m5 is a potent small molecule inhibitor of the Sonic Hedgehog/PTCH1 interaction, binding Shh with a Kd of 170 nM. It blocks Hedgehog pathway activation and Gli-mediated transcription (IC50 = 230 nM), making it a valuable tool for studying this signaling axis in both cellular and animal models of development and disease.
Field of Research
Pharmacology & Drug Discovery, Stem Cell & Developmental Biology
Molecular Weight
1632.83
Storage Conditions
-20°C
Notes
For research use only.

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