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Recombinant Human IL-5 protein

CAT: 0772-CD01492-01Size: 2 µgDry Ice: NoHazardous: No
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CAT#:0772-CD01492-01Size:2 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The IL-5 gene is located on chromosome 5 in humans, in close proximity to the genes encoding IL-3, IL-4, and granulocyte-macrophage colony-stimulating factor (GM-CSF), which are often co-expressed in TH2 cells. Through binding to the IL-5 receptor, IL-5 stimulates B cell growth and increases immunroglobulin secretion. It is also a key mediator in eosinophil activation. Interleukin-5 has long been associated with the cause of several allergic diseases including allergic rhinitis and asthma. IL-5 is a 115-amino acid (in human, 133 in the mouse) -long TH2 cytokine that is part of the hematopoietic family. Unlike other members of this cytokine family (namely IL-3 and GM-CSF), this glycoprotein in its active form is a homodimer.
CAS Number
9000-83-3
Molecular Weight
Approximately 26.5 kDa, a disulfide-linked homodimeric protein containing two 116 amino acids.

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