Recombinant Mouse Exodus-2/CCL21 protein

• Background:

  CCL21 is encoded by CCL21 gene that is located in Chr. 4 and shows 21-33 % identity to other CC chemokines. This chemokine contains the four conserved cysteines characteristic of β chemokines plus two additional cysteines in its unusually long carboxylterminal domain. Human and mouse CCL21 are highly conserved, exhibiting 86 % amino acid sequence identity. CCL21 is highly expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. It elicits effects by binding with CCR7, having functions of T and B lymphocytes chemotaxis and inhibiting hematopoiesis.

• Molecular Weight:

  Approximately 12.1 kDa, a single, non-glycosylated polypeptide chain containing 11 amino acids.

• CAS Number:

  9000-83-3