Recombinant Mouse MCP-3/CCL7 protein

Recombinant Mouse MCP-3/CCL7 protein

• Background: Mouse CCL7, also known as MARC, is belonging to the CC chemokine family. It is encoded by the gene CCL7 and was isolated from a mouse mast cell line after Fc epsilon RI triggering by IgE plus antigen. Sequence comparisons suggest that MARC may be the mouse homologue of the human MCP-3 gene. Similar to the human system, MARC/FIC is postulated the Mouse MCP-3. The MCP-3 protein family signals through CCR2 expect MCP-1 and possess cross-reacts across species. CCL7/MCP3 has chemotactic fuction for monocytes and eosinophils, but not for neutrophils.
• CAS Number: 9000-83-3
• Reconstitution: Lyophilized from a .2 μm filtered concentrated solution in 2 mM PB, pH 7.4, 15 mM NaCl.
• Molecular Weight: Approximately 8.5 kDa, a single, non-glycosylated polypeptide chain containing 74 amino acids.