Recombinant Mouse SDF-1 Alpha/CXCL12 Alpha protein

Recombinant Mouse SDF-1 Alpha/CXCL12 Alpha protein

• Background: CXCL12 also known as SDF-1 is belonging to the CXC chemokine family. Mouse CXCL12 is expressed as two isoforms that differ only in the C-terminal tail. Both SDF-1 isoforms undergo proteolytic processing of the first two N-terminal amino acids. Contrast to SDF-1β, SDF-1α is shorter by four amino acids at the C-terminal tail. On the cell surface, the receptor for this chemokine is CXCR4 and syndecan4. CXCL12 is strongly chemotactic for T-lymphocytes, monocytes, but not neutrophils. SDF-1 is highly conserved between species, Mouse CXCL12α shares approximately 93 % amino acid sequence identity with human CXCL12α.
• CAS Number: 9000-83-3
• Reconstitution: Lyophilized from a .2 μm filtered solution of 2mM PB, 15mM NaCl, pH 7.4.
• Molecular Weight: Approximately 8. kDa, a single non-glycosylated polypeptide chain containing 68 amino acids.