Recombinant Rhesus Macaque IL-1 Alpha protein

Recombinant Rhesus Macaque IL-1 Alpha protein

• Background: Interleukin-1 alpha (IL-1α) is a non-secreted proinflammatory cytokine produced mainly by activated macrophages, as well as neutrophils, epithelial cells, and endothelial cells. It possesses metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. Both IL-1α and IL-1β binds to the same receptor and has similar identical biological properties. Among various species, the amino acid sequence of mature IL-1α is conserved 60 % to 70 %. IL-1α recently started to find effective application in cosmetic and dermatological formulations, which allow to significantly harmonizing derma architecture.
• CAS Number: 9000-83-3
• Reconstitution: Lyophilized from a .2 μm filtered concentrated solution in PBS, pH 7.4, 3% trehalose.
• Molecular Weight: Approximately 18.1 kDa, a single non-glycosylated polypeptide chain containing 159 amino acids.