Recombinant Rhesus Macaque G-CSF protein

• Background:

  Granulocyte colony stimulating factor (G-CSF) is a pleiotropic cytokine and mainly produced by monocytes and macrophages upon activation by endotoxin, TNF-α and IFN-γ. Besides, many other cell types can secreted this protein after LPS, IL-1 or TNF-α activation, which are fibroblasts, endothelial cells, astrocytes and bone marrow stromal cells. Various carcinoma cell lines and myeloblastic leukemia cells can express G-CSF constitutively. G-CSF is cytokine that acts in hematopoiesis by controlling the production, differentiation, and function of 2 related white cell populations of the blood, the granulocytes and the monocytes-macrophages. In addition it may function in some adhesion or recognition events at the cell surface.

• CAS Number:

  9000-83-3

• Reconstitution:

  Lyophilized from a .2 μm filtered solution of PBS, pH 7.4.

• Molecular Weight:

  Approximately 18.9 kDa, a single non-glycosylated polypeptide chain containing 174 amino acids.