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MAPK13-IN-1

CAT: 0804-HY-18850-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-18850-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MPAK13-IN-1 is a MAPK13 (p38δ) inhibitor, with an IC50 of 620 nM.
CAS Number
229002-10-2
UNSPSC
12352005
Target
Autophagy; p38 MAPK
Type
Reference compound
Related Pathways
Autophagy; MAPK/ERK Pathway
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/MAPK13-IN-1.html
Purity
98.88
Solubility
DMSO : ≥ 250 mg/mL
Smiles
O=C(NC1=CC=C(OC2=CC=NC=C2)C=C1)NC3=CC(C(C)(C)C)=NN3C
Molecular Formula
C20H23N5O2
Molecular Weight
365.43
References & Citations
[1]Yurtsever Z, et al. First comprehensive structural and biophysical analysis of MAPK13 inhibitors targeting DFG-in and DFG-out binding modes. Biochim Biophys Acta. 2016 Nov;1860 (11 Pt A) :2335-2344.|[2]Mehdi Bouhaddou, et al. The Global Phosphorylation Landscape of SARS-CoV-2 Infection. Cell. 2020 Aug 6;182 (3) :685-712.e19.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
MAPK13