Bromodiphenhydramine (hydrochloride)

• UNSPSC Description:

  Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research[1][2][3].

• Target Antigen:

  Bacterial; Histamine Receptor

• Type:

  Reference compound

• Related Pathways:

  Anti-infection;GPCR/G Protein;Immunology/Inflammation;Neuronal Signaling

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection; Inflammation/Immunology

• Assay Protocol:

  https://www.medchemexpress.com/bromodiphenhydramine-hydrochloride.html

• Purity:

  97.34

• Solubility:

  DMSO : 125 mg/mL (ultrasonic)|H2O : 3.33 mg/mL (ultrasonic;warming;heat to 60°C)

• Smiles:

  BrC1=CC=C(C(C2=CC=CC=C2)OCCN(C)C)C=C1.[H]Cl

• Molecular Weight:

  370.71

• References & Citations:

  [1]MOLINA EB. [A new antihistaminic, bromodiphenhydramine hydrochloride, in the control of cutaneous allergies]. Sem Med. 1960 Jul 11;117:151-2. Spanish. |[2]Dastidar SG, et al. Antibacterial activity of ambodryl and benadryl. J Appl Bacteriol. 1976 Oct;41(2):209-14.|[3]Ray S, et al. Studies on synergism between penicillins and ambodryl (bromodiphenhydramine HCl), an antihistamine with antimicrobial property. Indian J Exp Biol. 1990 Mar;28(3):253-8.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  4°C (Powder, sealed storage, away from moisture)

• Clinical Information:

  Launched

• CAS Number:

  1808-12-4