APC-Labeled Monoclonal Anti-FMC63 Antibody, Rabbit IgG (1G10) (0.03% Proclin)

• Background:

  FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

• Description:

  Monoclonal Anti-FMC63 Antibody, Rabbit IgG (1G10) is a neutralizing rabbit monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply. It shows superior performance in flow cytometry assays with higher affinity and better specificity.

• Host:

  HEK293

• Target:

  FMC63

• Conjugation:

  APC Labeled

• Tag:

  Rabbit IgG | Rabbit Kappa

• Applications:

  Flow Cytometry (Evaluation of Anti-CD19 (FMC63 scFv) CAR Expression) .

• Stability:

  ● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months after reconstitution. ● 2-8 °C for 12 months after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please protect from light and avoid repeated freeze-thaw cycles.

• Format:

  Powder

• Buffer:

  PBS, pH7.4,0.2% BSA, 0.03% Proclin300

• Additives:

  Trehalose

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C, aviod light

• Package Size:

  25tests*1

• Species:

  Rabbit