APC-Labeled Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (Y45) (Site-specific conjugation)

• Background:

  FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.

• Description:

  APC-Labeled Monoclonal Anti-FMC63 Antibody, Mouse IgG1 is a neutralizing antibody produced via site-specific conjugation of APC to Monoclonal Anti-FMC63 Antibody, Mouse IgG1 under optimal conditions with a proprietary technology. We also carry another proclin-containing version of APC-Labeled Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (FM3-AY54A1) produced with the same production process except for proclin, and the proclin-containing product has the same performance and can be stored under 2-8 °C for no less than 12 months after reconstitution.

• Host:

  HEK293

• Origin Species:

  Mouse

• Target:

  FMC63

• Conjugation:

  APC Labeled

• Tag:

  Mouse IgG1 | Mouse Kappa

• Applications:

  Flow Cytometry (Evaluation of Anti-CD19 (FMC63 scFv) CAR Expression) . Please note that this product is NOT compatible to streptavidin detection system.

• Stability:

  ● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please protect from light and avoid repeated freeze-thaw cycles.

• Format:

  Powder

• Buffer:

  PBS, 0.5% BSA, pH7.4

• Additives:

  Trehalose

• Shipping Conditions:

  RT

• Storage Conditions:

  -20°C, aviod light

• Package Size:

  25tests*1

• Species:

  Mouse

• CAS Number:

  9007-83-4