Complement factor D Polyclonal Antibody
CAT:
866-RD89481A-02
Size:
120 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
Complement factor D Polyclonal Antibody
- Background: This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.
- Synonyms: CFD,ADIPSIN,ADN,DF,PFD
- Gene ID: 1675
- Swiss Prot: P00746
- Host: Rabbit
- Reactivity: Human
- Immunogen: Recombinant fusion protein of human Complement factor D
- Clonality: Polyclonal
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: WB
- Purification: Affinity purification
- Concentration: 1mg/mL
- Dilution: WB 1:500-1:2000
- Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
- Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- Calculated Molecular Weight: 33kDa
- Observed Molecular Weight: 34KDa