Complement factor D Polyclonal Antibody

• Background :

  This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.

• Description :

  This is a Complement factor D Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  CFD, ADIPSIN, ADN, DF, PFD

• Gene ID :

  1675

• Swiss Prot :

  P00746

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human Complement factor D

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  33kDa

• Observed Molecular Weight :

  34KDa

• Host or Source :

  Rabbit

• Isotype :

  IgG