Complement factor D Polyclonal Antibody

• Background:

  This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease.

• Description:

  This is a Complement factor D Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CFD, ADIPSIN, ADN, DF, PFD

• Gene ID:

  1675

• Swiss Prot:

  P00746

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human Complement factor D

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.05% proclin300,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33kDa

• Observed Molecular Weight:

  34KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG