(KO Validated) IGF1R Polyclonal Antibody
CAT:
866-RD86735A-02
Size:
120 μL
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
(KO Validated) IGF1R Polyclonal Antibody
- Background: This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
- Synonyms: IGF1R,CD221,IGFIR,IGFR,JTK13
- Gene ID: 3480
- Swiss Prot: P08069
- Host: Rabbit
- Reactivity: Human,Mouse,Rat
- Immunogen: A synthetic peptide of human IGF1R
- Clonality: Polyclonal
- Isotype: IgG
- Conjugation: Unconjugated
- Applications: WB
- Purification: Affinity purification
- Concentration: 1 mg/mL
- Dilution: WB 1:500-1:2000
- Buffer: PBS with 0.01% thiomersal,50% glycerol,pH7.3.
- Storage Conditions: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
- Calculated Molecular Weight: 21kDa/54kDa/57kDa
- Observed Molecular Weight: 57KDa