CLDN16 Polyclonal Antibody

CAT: 0866-RD90027A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD90027A-01Size:60 μL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure. This gene and the CLDN1 gene are clustered on chromosome 3q28.
Description
This is a CLDN16 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CLDN16, HOMG3, PCLN1
Gene ID
10686
Swiss Prot
Q9Y5I7
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human CLDN16
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
12kDa
Observed Molecular Weight
16kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RD82027A-01CLDN17 Polyclonal Antibody
RD89887A-01CLDN18 Polyclonal Antibody
RD89827A-01CLDN14 Polyclonal Antibody
RD268031A-01CLDN10 Polyclonal Antibody
RD89527A-01CLDN19 Polyclonal Antibody
RD253357A-01CLDN12 Polyclonal Antibody
RD267480A-01CLDN11 Polyclonal Antibody
RD79886A-01CLDND2 Polyclonal Antibody
RD77373A-01CLDND1 Polyclonal Antibody
RD253366A-01CLDN25 Polyclonal Antibody

Alternative Products

CatalogName
MBS2561261-01CLDN16 Polyclonal Antibody
TA334205CLDN16 Rabbit Polyclonal Antibody
TRV-0057781-01Polyclonal Antibody to Claudin 16 (CLDN16)
AP50943PU-NCLDN16 (N-term) Rabbit Polyclonal Antibody
27-910CLDN16 Antibody
STJ111904Anti-CLDN16 antibody
C47503CLDN16 Conjugated Antibody
abx171761-01Claudin 16 (CLDN16) Antibody
MBS9203270-01CLDN16 Antibody (N-term)
DF14223-BPCLDN16 Peptide

Popular Products