TFE3 Polyclonal Antibody

• Background:

  This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocations in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocation partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants.

• Description:

  This is a TFE3 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  TFE3, RCCP2, RCCX1, TFEA, bHLHe33

• Gene ID:

  7030

• Swiss Prot:

  P19532

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human TFE3

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  95kDa

• Observed Molecular Weight:

  120kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG