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GRM4 Polyclonal Antibody

CAT: 0866-RD89791A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89791A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities. Several transcript variants encoding different isoforms have been found for this gene.
Description
This is a GRM4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GRM4, GPRC1D, MGLUR4, mGlu4
Gene ID
2914
Swiss Prot
Q14833
Reactivity
Mouse, Rat
Immunogen
Recombinant fusion protein of human GRM4
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
55kDa/56kDa
Observed Molecular Weight
52kDa
Host or Source
Rabbit
Isotype
IgG

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