GRM1 Polyclonal Antibody

CAT: 0866-RD87332A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87332A-01Size:60 μL
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Background
This gene encodes a metabotropic glutamate receptor that functions by activating phospholipase C. L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The canonical alpha isoform of the encoded protein is a disulfide-linked homodimer whose activity is mediated by a G-protein-coupled phosphatidylinositol-calcium second messenger system. This gene may be associated with many disease states, including schizophrenia, bipolar disorder, depression, and breast cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
This is a GRM1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
GRM1, GPRC1A, MGLU1, MGLUR1, PPP1R85, SCAR13
Gene ID
2911
Swiss Prot
Q13255
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human GRM1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
104kDa
Observed Molecular Weight
125KDa
Host or Source
Rabbit
Isotype
IgG

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