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MCM10 Polyclonal Antibody

CAT: 0866-RD89788A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89788A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The hexameric protein complex formed by MCM proteins is a key component of the pre-replication complex (pre-RC) and it may be involved in the formation of replication forks and in the recruitment of other DNA replication related proteins. This protein can interact with MCM2 and MCM6, as well as with the origin recognition protein ORC2. It is regulated by proteolysis and phosphorylation in a cell cycle-dependent manner. Studies of a similar protein in Xenopus suggest that the chromatin binding of this protein at the onset of DNA replication is after pre-RC assembly and before origin unwinding. Alternatively spliced transcript variants encoding distinct isoforms have been identified.
Description
This is a MCM10 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MCM10, CNA43, DNA43, PRO2249
Gene ID
55388
Swiss Prot
Q7L590
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human MCM10
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
186kDa/192kDa
Observed Molecular Weight
192kDa
Host or Source
Rabbit
Isotype
IgG

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