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MacroH2A.1 Polyclonal Antibody

CAT: 0866-RD89469A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD89469A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4) . The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent histone that is a member of the histone H2A family. It replaces conventional H2A histones in a subset of nucleosomes where it represses transcription and participates in stable X chromosome inactivation. Alternative splicing results in multiple transcript variants encoding different isoforms.
Description
This is a macroH2A.1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
H2AFY, H2A.y, H2A/y, H2AF12M, MACROH2A1.1, mH2A1, macroH2A1.2, core histone macro-H2A.1
Gene ID
9555
Swiss Prot
O75367
Reactivity
Human
Immunogen
A synthetic peptide of human macroH2A.1
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.05% proclin300,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
32kDa/37kDa/38kDa
Observed Molecular Weight
38KDa
Host or Source
Rabbit
Isotype
IgG

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