IRF9 Polyclonal Antibody

• Background:

  Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta. Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1 are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.

• Description:

  This is a IRF9 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  IRF9, IRF-9, ISGF3, ISGF3G, p48, interferon regulatory factor 9

• Gene ID:

  10379

• Swiss Prot:

  Q00978

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human IRF9

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33kDa/35kDa/42kDa

• Observed Molecular Weight:

  48KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG