IRF9 Polyclonal Antibody

CAT: 0866-RD89379A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89379A-01Size:60 μL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcription factor that plays an essential role in anti-viral immunity. It mediates signaling by type I IFNs (IFN-alpha and IFN-beta. Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1 are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. IRF9/ISGF3G associates with the phosphorylated STAT1:STAT2 dimer to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE to activate the transcription of interferon stimulated genes, which drive the cell in an antiviral state.
Description
This is a IRF9 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
IRF9, IRF-9, ISGF3, ISGF3G, p48, interferon regulatory factor 9
Gene ID
10379
Swiss Prot
Q00978
Reactivity
Human
Immunogen
Recombinant fusion protein of human IRF9
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.02% sodium azide,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
33kDa/35kDa/42kDa
Observed Molecular Weight
48KDa
Host or Source
Rabbit
Isotype
IgG

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