IRF5 Polyclonal Antibody

• Background:

  IRF5, also named as SLEB10, contians one IRF tryptophan pentad repeat DNA-binding domain and belongs to the IRF family. I t is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection. It is activated by TLR7 or TLR8 signaling. Genetic variations in IRF5 are associated with susceptibility to inflammatory bowel disease type 14 (IBD14) and systemic lupus erythematosus type 10 (SLEB10) .

• Description:

  This is a IRF5 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Interferon regulatory factor 5, Interferon regulatory factor 5 bone marrow variant, IRF 5, IRF-5, Irf5, IRF5, SLEB10

• Swiss Prot:

  Q13568

• Accession Number:

  NP116032

• Reactivity:

  Human, Mouse

• Immunogen:

  Synthetic peptide of human IRF5

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.7 mg/mL

• Dilution:

  WB 1:500-1:2000, IHC 1:25-1:100, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  56 kDa

• Observed Molecular Weight:

  Refer to figures

• Host or Source:

  Rabbit

• Isotype:

  IgG