SETD4 Polyclonal Antibody

• Background:

  Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response. Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively, leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity. Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3, thereby promoting heterochromatin formation. Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs (By similarity.

• Description:

  This is a SETD4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  C21orf18, C21orf27, SETD4

• Gene ID:

  54093

• Swiss Prot:

  Q9NVD3

• Reactivity:

  Human, Mouse

• Immunogen:

  Recombinant fusion protein of human SETD4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  155kDa

• Observed Molecular Weight:

  155kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG