SETD4 Polyclonal Antibody

• Background :

  Histone-lysine N-methyltransferase that acts as a regulator of cell proliferation, cell differentiation and inflammatory response. Regulates the inflammatory response by mediating mono- and dimethylation of 'Lys-4' of histone H3 (H3K4me1 and H3K4me2, respectively, leading to activate the transcription of proinflammatory cytokines IL6 and TNF-alpha (By similarity. Also involved in the regulation of stem cell quiescence by catalyzing the trimethylation of 'Lys-20' of histone H4 (H4K20me3, thereby promoting heterochromatin formation. Involved in proliferation, migration, paracrine and myogenic differentiation of bone marrow mesenchymal stem cells (BMSCs (By similarity.

• Description :

  This is a SETD4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  C21orf18, C21orf27, SETD4

• Gene ID :

  54093

• Swiss Prot :

  Q9NVD3

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant fusion protein of human SETD4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  155kDa

• Observed Molecular Weight :

  155kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG