SETD2 Polyclonal Antibody

• Background :

  Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein belonging to a class of huntingtin interacting proteins characterized by WW motifs. This protein is a histone methyltransferase that is specific for lysine-36 of histone H3, and methylation of this residue is associated with active chromatin. This protein also contains a novel transcriptional activation domain and has been found associated with hyperphosphorylated RNA polymerase II.

• Description :

  This is a SETD2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  EC 2.1.1.43, FLJ16420, FLJ22472, FLJ23184, FLJ45883, HBP231, HIF 1, HIF-1, HIF1, HIP-1, Histone lysine N methyltransferase SETD2, Histone-lysine N-methyltransferase SETD2, hSET2, HSPC069, Huntingtin interacting protein 1, Huntingtin interacting protein, Huntingtin intera

• Swiss Prot :

  Q9BYW2

• Accession Number :

  BC117162

• Reactivity :

  Human, Mouse

• Immunogen :

  Recombinant protein of human SETD2

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  IHC, ELISA

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  0.2 mg/mL

• Dilution :

  IHC 1:50-1:200

• Buffer :

  PBS with 0.05% sodium azide and 50% glycerol, PH7.4

• Storage Conditions :

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source :

  Rabbit

• Isotype :

  IgG