Products for Research Use Only

RNF185 Polyclonal Antibody

CAT: 0866-RD88495A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD88495A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Acts in the endoplasmic reticulum (ER-associated degradation (ERAD pathway, which targets misfolded proteins that accumulate in the endoplasmic reticulum (ER for ubiquitination and subsequent proteasome-mediated degradation. Protects cells from ER stress-induced apoptosis. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2.
Description
This is a RNF185 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
RNF185
Gene ID
91445
Swiss Prot
Q96GF1
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human RNF185
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
86kDa/105kDa/111kDa/120kDa
Observed Molecular Weight
130kDa
Host or Source
Rabbit
Isotype
IgG