RNF111 Polyclonal Antibody

• Background:

  The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.

• Description:

  This is a RNF111 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ARK, Arkadia, DKFZp313E0731, DKFZp686H1966, DKFZp761D081, E3 ubiquitin protein ligase Arkadia, E3 ubiquitin-protein ligase Arkadia, FLJ38008, RING finger protein 111, RN111, RNF 111, RNF111

• Swiss Prot:

  Q6ZNA4

• Accession Number:

  BC010369

• Reactivity:

  Human

• Immunogen:

  Fusion protein of human RNF111

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.84 mg/mL

• Dilution:

  IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG