RNF111 Polyclonal Antibody

CAT: 0866-RD218773A-01Size: 20 µLDry Ice: NoHazardous: No
CAT#:0866-RD218773A-01Size:20 µL
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a nuclear RING-domain containing E3 ubiquitin ligase. This protein interacts with the transforming growth factor (TGF) -beta/NODAL signaling pathway by promoting the ubiquitination and proteosomal degradation of negative regulators, like SMAD proteins, and thereby enhances TGF-beta target-gene transcription. As a modulator of the nodal signaling cascade, this gene plays a critical role in the induction of mesoderm during embryonic development. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
Description
This is a RNF111 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
ARK, Arkadia, DKFZp313E0731, DKFZp686H1966, DKFZp761D081, E3 ubiquitin protein ligase Arkadia, E3 ubiquitin-protein ligase Arkadia, FLJ38008, RING finger protein 111, RN111, RNF 111, RNF111
Swiss Prot
Q6ZNA4
Accession Number
BC010369
Reactivity
Human
Immunogen
Fusion protein of human RNF111
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
IHC, ELISA
Purification Method
Antigen affinity purification
Assay Type
Antibody
Concentration
0.84 mg/mL
Dilution
IHC 1:50-1:300, ELISA 1:5000-1:10000
Buffer
PBS with 0.05% NaN3 and 40% Glycerol, pH7.4
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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