MASP2 Polyclonal Antibody

• Background:

  This gene encodes a member of the peptidase S1 family of serine proteases. The encoded preproprotein is proteolytically processed to generate A and B chains that heterodimerize to form the mature protease. This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system. The encoded protease also plays a role in the coagulation cascade through cleavage of prothrombin to form thrombin. Myocardial infarction and acute stroke patients exhibit reduced serum concentrations of the encoded protein. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

• Description:

  This is a MASP2 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  MASP2, MAP19, MASP-2, MASP1P1, sMAP

• Gene ID:

  10747

• Swiss Prot:

  O00187

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human MASP2

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  49kDa/51kDa

• Observed Molecular Weight:

  46kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG