ASH2L Polyclonal Antibody

• Background:

  Transcriptional regulator. Component or associated component of some histone methyltransferase complexes which regulates transcription through recruitment of those complexes to gene promoters. Component of the Set1/Ash2 histone methyltransferase (HMT complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May play a role in hematopoiesis. In association with RBBP5 and WDR5, stimulates the histone methyltransferase activities of KMT2A, KMT2B, KMT2C, KMT2D, SETD1A and SETD1B.

• Description:

  This is a ASH2L Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ASH2L, ASH2, ASH2L1, ASH2L2, Bre2

• Gene ID:

  9070

• Swiss Prot:

  Q9UBL3

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human ASH2L

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  61kDa/63kDa

• Observed Molecular Weight:

  61kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG