NRARP Polyclonal Antibody

CAT: 0866-RD87572A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD87572A-01Size:60 μL
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Background
Downstream effector of Notch signaling. Involved in the regulation of liver cancer cells self-renewal. Involved in angiogenesis acting downstream of Notch at branch points to regulate vascular density. Proposed to integrate endothelial Notch and Wnt signaling to control stalk cell proliferation and to stablilize new endothelial connections during angiogenesis. During somitogenesis involved in maintenance of proper somite segmentation and proper numbers of somites and vertebrae. Required for proper anterior-posterior somite patterning. Proposed to function in a negative feedback loop to destabilize Notch 1 intracellular domain (NICD and downregulate the Notch signal, preventing expansion of the Notch signal into the anterior somite domain (By similarity.
Description
This is a NRARP Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
NRARP
Gene ID
441478
Swiss Prot
Q7Z6K4
Reactivity
Mouse
Immunogen
Recombinant fusion protein of human NRARP
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
34kDa
Observed Molecular Weight
34kDa
Host or Source
Rabbit
Isotype
IgG

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