RNF166 Polyclonal Antibody

• Background :

  E3 ubiquitin-protein ligase that promotes the ubiquitination of different substrates. In turn, participates in different biological processes including interferon production or autophagy. Plays a role in the activation of RNA virus-induced interferon-beta production by promoting the ubiquitination of TRAF3 and TRAF6. Plays also a role in the early recruitment of autophagy adapters to bacteria. Mediates 'Lys-29' and 'Lys-33'-linked ubiquitination of SQSTM1 leading to xenophagic targeting of bacteria and inhibition of their replication.

• Description :

  This is a RNF166 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  RNF166

• Gene ID :

  115992

• Swiss Prot :

  Q96A37

• Reactivity :

  Human, Mouse

• Immunogen :

  A synthetic peptide of human RNF166

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  87kDa

• Observed Molecular Weight :

  100kDa

• Host or Source :

  Rabbit

• Isotype :

  IgG