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C-Myc Polyclonal Antibody

CAT: 0866-RD86768A-01Size: 60 μLDry Ice: NoHazardous: No
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CAT#:0866-RD86768A-01Size:60 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a multifunctional, nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. It functions as a transcription factor that regulates transcription of specific target genes. Mutations, overexpression, rearrangement and translocation of this gene have been associated with a variety of hematopoietic tumors, leukemias and lymphomas, including Burkitt lymphoma. There is evidence to show that alternative translation initiations from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site result in the production of two isoforms with distinct N-termini. The synthesis of non-AUG initiated protein is suppressed in Burkitt's lymphomas, suggesting its importance in the normal function of this gene.
Description
This is a c-Myc Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
MRTL, MYCC, bHLHe39, c-Myc, MYC
Gene ID
4609
Swiss Prot
P01106
Reactivity
Human, Mouse
Immunogen
A synthetic peptide of human c-Myc
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1 mg/mL
Dilution
WB 1:500-1:2000
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
44kDa
Observed Molecular Weight
46KDa
Host or Source
Rabbit
Isotype
IgG

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