ATF4 Polyclonal Antibody

• Background :

  This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2) . The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

• Description :

  This is a ATF4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  ATF4, CREB-2, CREB2, TAXREB67, TXREB

• Gene ID :

  468

• Swiss Prot :

  P18848

• Reactivity :

  Human

• Immunogen :

  Recombinant fusion protein of human ATF4

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  19kDa/21kDa

• Observed Molecular Weight :

  27KDa

• Host or Source :

  Rabbit

• Isotype :

  IgG