ATF4 Polyclonal Antibody

• Background:

  This gene encodes a transcription factor that was originally identified as a widely expressed mammalian DNA binding protein that could bind a tax-responsive enhancer element in the LTR of HTLV-1. The encoded protein was also isolated and characterized as the cAMP-response element binding protein 2 (CREB-2) . The protein encoded by this gene belongs to a family of DNA-binding proteins that includes the AP-1 family of transcription factors, cAMP-response element binding proteins (CREBs) and CREB-like proteins. These transcription factors share a leucine zipper region that is involved in protein-protein interactions, located C-terminal to a stretch of basic amino acids that functions as a DNA binding domain. Two alternative transcripts encoding the same protein have been described. Two pseudogenes are located on the X chromosome at q28 in a region containing a large inverted duplication.

• Description:

  This is a ATF4 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  ATF4, CREB-2, CREB2, TAXREB67, TXREB

• Gene ID:

  468

• Swiss Prot:

  P18848

• Reactivity:

  Human

• Immunogen:

  Recombinant fusion protein of human ATF4

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000

• Buffer:

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  19kDa/21kDa

• Observed Molecular Weight:

  27KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG