Recombinant MHC Class I Monoclonal Antibody

• Background:

  Major histocompatibility complex (MHC) molecules form an integral part of the immune response system. They are cell-surface receptors that bind peptides and present them to T lymphocytes. HLA-A, -B and -C encode membrane anchored heavy chains which heterodimerize with a light chain (b-2-Microglobulin) to form MHC-I. Polymorphisms yield hundreds of HLA-A, -B and -C alleles.

• Synonyms:

  HLA class I histocompatibility,HLA A,HLA B

• Swiss Prot:

  P30450

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  A synthesized peptide derived from human MHC class I

• Clonality:

  Monoclonal

• Isotype:

  IgG

• Conjugation:

  Unconjugated

• Applications:

  WB,IHC-P

• Purification:

  Affinity purification

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:1000-1:2000, IHC 1:50-1:100

• Buffer:

  50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  13kDa

• Observed Molecular Weight:

  15/20kDa