Recombinant FKBP52 Monoclonal Antibody

• Background:

  FKBP52 (FK506 binding protein 4) is a member of the immunophilin protein family that comprises intracellular protein effectors of immunosuppressive drugs, and it is known as a steroid receptor-associated protein. As a novel regulator of microtubule dynamics, FKBP52 is associated with the motor protein dynein and with the cytoskeleton during mitosis. FKBP52 is highly expressed in CNS regions susceptible to Alzheimer's, and plays a role in modulating toxicity of Abeta peptides. The protein can associate with the Tau function, and may help to decipher and modulate the events involved in Tau-induced neurodegeneration. In addition, FKBP52 is likely to play a role in growth and development of the male genitalia.

• Description:

  This is a Recombinant FKBP52 Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  51 kDa FK506-binding protein,52 kDa FK506 binding protein,52 kDa FK506-binding protein,52 kDa FKBP,59 kDa immunophilin, FK506 binding protein 4, FK506-binding protein 4, FKBP 4, FKBP 52, FKBP 59, FKBP-4, FKBP-52, FKBP4, FKBP4, FKBP51, FKBP52 protein, FKBP59, HBI, Hsp 5

• Gene ID:

  2288

• Swiss Prot:

  Q02790

• Reactivity:

  Human, Mouse, Rat, Hamster

• Immunogen:

  A synthetic peptide of human FKBP52

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:1000-1:5000, IF 1:20-1:50

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  58kDa

• Observed Molecular Weight:

  58kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG