Recombinant Cytochrome C Monoclonal Antibody

• Background:

  Cytochrome c is a 12-15 kDa electron transporting protein located in the inner mitochondrial membrane. Upon apoptotic stimulation, cytochrome c can be released from mitochondria into cytoplasm, resulting in caspase-3 activation and apoptosis. Measurement of cytochrome c release from the mitochondria is useful for detection of the onset of apoptosis in cells. In addition, cytochrome c can also leave cells and be detectable in extra-cellular medium of apoptotic cells and serum of cancer patients. The level of serum cytochrome c may serve as a prognostic maker during cancer therapy.

• Description:

  This is a Recombinant Cytochrome C Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Cytochrome C, Somatic, CYC, Cytochrome C, THC4, HCS

• Gene ID:

  54205

• Swiss Prot:

  P99999

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide of human Cytochrome C

• Clonality:

  Monoclonal

• Conjugation:

  Unconjugated

• Type:

  Recombinant Antibody

• Applications:

  WB, IHC-P

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:1000-1:2000, IHC 1:50-1:100

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  47kDa

• Observed Molecular Weight:

  47kDa

• Host or Source:

  Rabbit

• Isotype:

  IgG