Recombinant Cytochrome P450 2D6 Monoclonal Antibody

• Background:

  CYP2D6 (Cytochrome P450 2D6) is also named as CYP2DL1 and belongs to the cytochrome P450 family. It is a monooxygenase that involved in the metabolism of drugs such as antiarrhythmics, adrenoceptor antagonists, and tricyclic antidepressants. CYP2D6 is responsible for the metabolism of many drugs and environmental chemicals that it oxidizes. It has 2 isoforms produced by alternative splicing with the molecular weight of 56 kDa and 50 kDa.

• Abbreviation:

  Cytochrome P450 2D6

• UniProt:

  P10635

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant protein of human CYP2D6

• Target:

  CPD6; CYP2D; CYP2D6; CYP2D7AP; CYP2D7BP; CYP2D7P2; CYP2D8P2; CYP2DL1; CYPIID6; Cytochrome P450 DB1; Cytochrome P450 family 2 subfamily D member 6; Cytochrome P450 family 2 subfamily D polypeptide 6; Debrisoquine 4 hydroxylase; Flavoprotein linked monooxygenase; Microsomal monooxygenase; P450 DB1; P450C2D; P450DB1; Xenobiotic monooxygenase

• Clonality:

  Monoclonal

• Clone:

  R07-3G8

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC-P; IF

• Field of Research:

  Cardiovascular; Metabolism; Signal Transduction

• Purification:

  Affinity Purified

• Concentration:

  300 μg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:50-1:100; IF 1:50-1:100

• Buffer:

  50mM Tris-Glycine (pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% protective protein

• Shipping Conditions:

  The product is shipped with ice pack, upon receipt, store it immediately at the temperature recommended.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  56kDa

• Observed Molecular Weight:

  50kDa

• Isotype:

  IgG