DSG1 Polyclonal Antibody

• Background :

  This gene encodes a member of the desmoglein protein subfamily. Desmogleins, along with desmocollins, are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. This gene is found in a cluster with other desmoglein family members on chromosome 18. The encoded protein has been identified as a target of auto-antibodies in the autoimmune skin blistering disease pemphigus foliaceus. Disruption of this gene has also been associated with the skin diseases palmoplantar keratoderma and erythroderma.

• Description :

  This is a DSG1 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms :

  DSG1, CDHF4, DG1, DSG, EPKHE, EPKHIA, PPKS1, SPPK1

• Gene ID :

  1828

• Swiss Prot :

  Q02413

• Reactivity :

  Human, Rat

• Immunogen :

  Recombinant fusion protein of human DSG1

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Polyclonal Antibody

• Applications :

  WB, IF

• Purification Method :

  Affinity purification

• Assay Type :

  Antibody

• Concentration :

  1 mg/mL

• Dilution :

  WB 1:500-1:2000, IF 1:50-1:100

• Buffer :

  PBS with 0.02% sodium azide,50% glycerol, pH7.3.

• Storage Conditions :

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight :

  44kDa/57kDa

• Observed Molecular Weight :

  38-45KDa

• Host or Source :

  Rabbit

• Isotype :

  IgG