CD68 Polyclonal Antibody

• Background:

  This gene encodes a 110-kD transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It is a member of the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family. The protein primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. It is a type I integral membrane protein with a heavily glycosylated extracellular domain and binds to tissue- and organ-specific lectins or selectins. The protein is also a member of the scavenger receptor family. Scavenger receptors typically function to clear cellular debris, promote phagocytosis, and mediate the recruitment and activation of macrophages. Alternative splicing results in multiple transcripts encoding different isoforms.

• Description:

  This is a CD68 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  CD68, GP110, LAMP4, SCARD1

• Gene ID:

  968

• Swiss Prot:

  P34810

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Recombinant fusion protein of human CD68

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  WB, IF

• Purification Method:

  Affinity purification

• Assay Type:

  Antibody

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000, IF 1:50-1:200

• Buffer:

  PBS with 0.01% thiomersal,50% glycerol, pH7.3.

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  8kDa/13kDa/15kDa/16kDa/18kDa

• Observed Molecular Weight:

  16KDa

• Host or Source:

  Rabbit

• Isotype:

  IgG