DUSP6 Polyclonal Antibody

CAT: 0866-RD89547A-01Size: 60 μLDry Ice: NoHazardous: No
CAT#:0866-RD89547A-01Size:60 μL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK2, is expressed in a variety of tissues with the highest levels in heart and pancreas, and unlike most other members of this family, is localized in the cytoplasm. Mutations in this gene have been associated with congenital hypogonadotropic hypogonadism. Alternatively spliced transcript variants have been found for this gene.
Description
This is a DUSP6 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
DUSP6, HH19, MKP3, PYST1
Gene ID
1848
Swiss Prot
Q16828
Reactivity
Human, Mouse, Rat
Immunogen
Recombinant fusion protein of human DUSP6
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Polyclonal Antibody
Applications
WB, IHC, IF
Purification Method
Affinity purification
Assay Type
Antibody
Concentration
1mg/mL
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, IF 1:50-1:200
Buffer
PBS with 0.01% thiomersal,50% glycerol, pH7.3.
Storage Conditions
Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Calculated Molecular Weight
61kDa
Observed Molecular Weight
65kDa
Host or Source
Rabbit
Isotype
IgG

Related Products

CatalogName
RDSA66714DUSP6 Rabbit mAb
RD-DUSP6-Hu-48TestsHuman Dual Specificity Phosphatase 6 (DUSP6) ELISA Kit
RDR-DUSP6-Hu-96TestsHuman Dual Specificity Phosphatase 6 (DUSP6) ELISA Kit
RD252886A-01DUSP7 Polyclonal Antibody
RD78490A-01DUSP8 Polyclonal Antibody
RD265745A-01DUSP5 Polyclonal Antibody
RD80257A-01DUSP16 Polyclonal Antibody
RD79012A-01DUSP2 Polyclonal Antibody
RD-DUSP6-Hu-01Human Dual Specificity Phosphatase 6 (DUSP6) ELISA Kit
RDR-DUSP6-Hu-48TestsHuman Dual Specificity Phosphatase 6 (DUSP6) ELISA Kit

Alternative Products

CatalogName
MBS8566173-01DUSP6 Polyclonal Antibody
MBS8596993-01DUSP6 rabbit polyclonal antibody
TA348992DUSP6 Goat Polyclonal Antibody
PHH38301Anti-DUSP6 Polyclonal Antibody

Popular Products