DUSP7 Polyclonal Antibody

• Background:

  Dual-specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP7 belongs to a class of DUSPs, designated MKPs, that dephosphorylate MAPK (mitogen-activated protein kinase) proteins ERK (see MIM 601795), JNK (see MIM 601158), and p38 (see MIM 600289) with specificity distinct from that of individual MKP proteins. MKPs contain a highly conserved C-terminal catalytic domain and an N-terminal Cdc25 (see MIM 116947) -like (CH2) domain. MAPK activation cascades mediate various physiologic processes, including cellular proliferation, apoptosis, differentiation, and stress responses (summary by Patterson et al., 2009 [PubMed 19228121]) .

• Description:

  This is a DUSP7 Polyclonal Antibody from Reddot Biotech. This product is for Research Use Only.

• Synonyms:

  Dual specificity phosphatase 7, Dual specificity protein phosphatase 7, Dual specificity protein phosphatase PYST2, DUS7, Dusp7, Jnk Stimulatory Phosphatase 1, JSP1, MAP kinase phosphatase X, MKPX, PYST2

• Swiss Prot:

  Q16829

• Accession Number:

  BC019107

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Fusion protein of human DUSP7

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Polyclonal Antibody

• Applications:

  IHC, ELISA

• Purification Method:

  Antigen affinity purification

• Assay Type:

  Antibody

• Concentration:

  0.66 mg/mL

• Dilution:

  IHC 1:50-1:300, ELISA 1:5000-1:10000

• Buffer:

  PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

• Storage Conditions:

  Store at -20°C. Avoid freeze / thaw cycles.

• Host or Source:

  Rabbit

• Isotype:

  IgG